Variants
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rs1057518672

  • Pathogenic

Your Genotype

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Description

Our laboratory reported two molecular diagnoses, a variant in SOX11 (NM_003108.3:c.1286G>A) and a 17q11.2 duplication, in an individual with delayed motor milestones, delayed speech, intellectual disability, autism, attention deficit hyperactivity disorder, aggression, oppositional defiant disorder, episodes of staring spells, and mild dysmorphic features (incomplete synophrys and short pedal digits).

Reference Allele

G


Alternative Allele

A

Chromosome

2


Location

5694007


Variant Type

SNP

Genes

ClinVar

Name

NM_003108.4(SOX11):c.1286G>A (p.Trp429Ter)


Allele

A


Clinical Significance

Pathogenic

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