Variants
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rs727503044

  • Uncertain significance

Your Genotype

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Description

The Arg468Gly variant in EYA1 has not been reported in individuals with hearing loss or in large population studies. Computational analyses (biochemical amino a cid properties, conservation, AlignGVGD, PolyPhen2, and SIFT) do not provide str ong support for or against an impact to the protein. Additional information is n eeded to fully assess the clinical significance of the Arg468Gly variant.

Reference Allele

T


Alternative Allele

C

Chromosome

8


Location

71215687


Variant Type

SNP

Genes

Phenotypes

ClinVar

Name

NM_000503.6(EYA1):c.1402A>G (p.Arg468Gly)


Allele

C


Clinical Significance

Uncertain significance

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