ClinVar updates for saved reports

Analyze onceStay current as ClinVar changes

Upload your raw DNA or sequencing file. Biocodify turns it into a searchable report you can keep current with ClinVar updates, reclassification alerts, and change history.

See how it works · Prefer a one-time report? Start with Starter

Monthly ClinVar refresh

Saved reports can be re-annotated whenever new ClinVar releases arrive.

Email when labels change

Get notified when a variant is reclassified so you know what changed.

Keep your latest snapshot

If you cancel later, the newest report snapshot remains available in your account.

ClinVar 2026-02 synced to your saved report

1 variant upgraded to Pathogenic, 3 new ClinVar labels added

Update history ready

Saved Variant Report

4,234,891 total variants, 47,392 with ClinVar annotation

Active filters:Changed in latest releaseClinVar only
4 results changed in the latest syncShowing 1-4 of 4
chr3
38,589,553
rs199473146
Het
SCN5A
VUSPathogenic
Reclassified in the latest ClinVar release
chr7
117,559,593
rs113993960
Hom
CFTR
No entryNew ClinVar label
Fresh annotation added without re-uploading your file
chr19
11,224,088
rs28942078
Het
LDLR
Review note updated
History keeps both the old and new ClinVar interpretations
Latest release highlights
ClinVar Updates

ClinVar keeps changing. Your saved report can keep up.

ClinVar classifications change over time. Starter + Updates keeps the same saved report current with new monthly releases, surfaces what changed, and lets you review old versus new labels without uploading your file again.

Monthly re-annotation

Saved reports are refreshed when new ClinVar data is released.

Visible change history

Compare old and new ClinVar labels release by release.

Email notifications

Get alerted when a variant classification changes.

Latest snapshot stays

If you cancel later, your newest report snapshot remains available.

Start with a one-time report if you want a snapshot. Choose Starter + Updates if you want the same report revisited whenever ClinVar changes.

See plan details
ClinVar Update History

ClinVar 2026-01 2026-02

Monthly refresh completed for this saved report.

Synced

12

total changes

1

pathogenic upgrade

3

new ClinVar labels

Reclassification

SCN5A

Pathogenic
VUSPathogenic

Shown in release history and highlighted in email notifications.

New annotation

CFTR

New label
No ClinVar entryNew ClinVar label

Added to the same saved report without another upload.

Review detail changed

LDLR

Updated
Previous noteUpdated note

Old and new ClinVar interpretations remain visible in history.

Email alert sent

You have 1 important reclassification to review.

Updates active

Works with data from

23andMeAncestry DNANebula GenomicsFamily Tree DNAMyHeritageSequencing.comNucleus Genomics
Any VCFAny 23andMe-like TXT

All company names are trademarks of their respective owners. Biocodify is not affiliated with or endorsed by these companies.

.vcf

whole_genome.vcf

847 MB - 4.2M variants

##fileformat=VCFv4.2

#CHROM POS ID REF ALT QUAL ...

chr1 10177 rs367896724 A AC

chr1 10352 rs555500075 T TA

chr1 10616 rs376342519 C CG

chr1 13110 rs540538026 G A

chr1 13116 rs62635286 T G

...

+ 4,234,891 more rows

Hidden by others
99% ignored
rs367896724what's this?

4.2M variants

others show ~500

No annotations

Other platforms only show you a fraction

Most genomics platforms cherry pick a curated subset of your data. They decide what's "interesting" and hide the rest. Your file might contain millions of variants, but you only see a few hundred.

Biocodify shows 100% of your data, fully annotated. Every variant. Every chromosome. Nothing filtered out, nothing hidden.

How It Works

From raw file to a report you can revisit

Get Started in 3 Easy Steps

Upload once, annotate everything, and stay current when ClinVar changes.

1. Upload

Drag and drop your raw DNA or sequencing file. We support VCFs and compatible uploads from major consumer genetics providers.

2. Annotate & Explore

Every variant is enriched with reference labels, population frequencies, and gene information. Browse it all in a searchable variant report.

3. Stay Current

Choose Starter + Updates and the same saved report will be re-annotated when new ClinVar releases land, with email alerts when classifications change.

Pick Your Starting Point

Choose between a snapshot and an ongoing ClinVar subscription

New buyers who plan to revisit results usually start with Starter + Updates. It gives you the same searchable report, plus monthly ClinVar refreshes and reclassification alerts.

Starter

Best for a one-time snapshot

$49.99one-time

A one-time report using the ClinVar data available today.

  • One-time report with the current ClinVar release
  • Full variant browser with gene, rsID, and frequency filters
  • dbSNP, gnomAD, gene, and ClinVar annotations
  • Upgrade to updates later if you want ongoing refreshes
Start with Starter
Recommended

Starter + Updates

Best for ongoing monitoring

$69.99/year

A saved report that keeps up when ClinVar classifications change.

  • Everything in Starter for the same saved report
  • Monthly ClinVar re-annotation when new releases arrive
  • Email alerts for important reclassifications
  • Update history showing old vs new ClinVar labels
  • Keep your latest report snapshot if you cancel
Choose Starter + Updates

Already bought Starter? Add ClinVar updates for $20 today, then renew at $69.99/year.

See full pricing details

Built for people who already have raw DNA data

You downloaded your raw file and want to actually inspect it

You want to search by gene, rsID, frequency, or ClinVar

You want a saved report that gets re-annotated when ClinVar classifications change

Powerful Browsing Tools

Explore your data your way

Three specialized browsers to help you understand your genetic data from different angles.

Variant Browser
PathogenicClinVarRare
rs80357906Pathogenic

chr17:43094464 - BRCA1 - DNA repair

rs113993960VUS

chr7:117559593 - CFTR - Ion transport

Explore millions of variants

Browse all variants in your file with fast filtering, sorting, and search.

Filter by reference labels (Pathogenic, Benign, VUS from ClinVar)
Search by rsID, gene, or genomic position
Sort by population frequency or annotation attributes
No Sign Up Required

See it for yourself

Explore sample data in under 30 seconds.

Explore the Demo
Privacy First

Your data stays yours

We take privacy seriously. Your genetic information is protected at every step.

Encrypted storage

Your genetic data is encrypted at rest and in transit using industry-standard protocols.

One-click delete

Remove all your data permanently anytime from your account settings. No questions asked.

Never sold

We don't sell, share, or monetize your genetic data. Ever. Your data is yours alone.

Loved by users

What our users are saying

Real feedback from people exploring their genetic data on Biocodify

This is wonderful and unique. I have much respect for what you've built here.

Platform User

Thanks for the work you're doing in democratizing access to genetic data. It's appreciated.

Genetics Enthusiast

My rheumatologist loved the way the platform broke all the data down. He spent a good 30 minutes with me looking over the site, and the gene search feature made it super easy for him to double-check a list of gene mutations he was interested in.

Patient

I like your site better than others because it clearly shows pathogenic variants, and I can easily copy or search for the rs numbers. The functionality is much better for what I need.

Researcher

Start with a report that stays current.

Choose Starter + Updates for a searchable report plus monthly ClinVar refreshes, reclassification alerts, and visible change history for the same saved analysis.

Prefer a one-time snapshot? Start with Starter

Frequently
asked questions

Is my data safe?

Yes. Your genetic data is encrypted at rest and in transit. We never share or sell your data. You can delete everything with one click.

What file formats do you support?

We support raw data exports from 23andMe, Nebula Genomics, Sequencing.com, Nucleus Genomics, Ancestry DNA, MyHeritage, ftDNA and standard VCF files. Do you have something else? Contact us! We would love to support.

How is this different from my 23andMe results?

23andMe shows you a curated subset of your data with their own interpretations. Biocodify lets you explore your complete raw data annotated against public reference databases.

What happens if ClinVar changes one of my labels?

Starter + Updates re-annotates the same saved report when new ClinVar releases arrive, emails you when classifications change, and keeps a history of old versus new labels. Starter stays a one-time snapshot of the ClinVar data available when you generated the report.

Is this for research only?

Yes. Biocodify is a data exploration platform for genomic files and public reference annotations.

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