ABHD5 Gene
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
ALIAS SYMBOLS
CGI-58
NCIE2
Your Results
Sign InDescription
The ABHD5 gene provides instructions for making a protein that turns on (activates) an enzyme called adipose triglyceride lipase (ATGL). The ATGL enzyme plays a role in breaking down fats called triglycerides, which are the main source of stored energy in cells. Triglycerides are the major component of cell structures called lipid droplets (also called adiposomes). The ABHD5 protein and the ATGL enzyme are found on the surface of lipid droplets. Once activated, the ATGL enzyme breaks down triglycerides in these structures to provide energy for the body.
CHROMOSOME
3
LOCATION
p21.33
LOCUS TYPE
gene with protein product
VARIANTS
164
External Links
HGNC
Ensembl
NCBI
OMIM