ACOX1 Gene
acyl-CoA oxidase 1
ALIAS SYMBOLS
PALMCOX
Your Results
Sign InDescription
The ACOX1 gene provides instructions for making an enzyme called peroxisomal straight-chain acyl-CoA oxidase. This enzyme is found in sac-like cell structures (organelles) called peroxisomes, which contain a variety of enzymes that break down many different substances. The peroxisomal straight-chain acyl-CoA oxidase enzyme plays a role in the breakdown of certain fat molecules called very long-chain fatty acids (VLCFAs). Specifically, it is involved in the first step of a process called the peroxisomal fatty acid beta-oxidation pathway. This process shortens the VLCFA molecules by two carbon atoms at a time until the VLCFAs are converted to a molecule called acetyl-CoA, which is transported out of the peroxisomes for reuse by the cell.
CHROMOSOME
17
LOCATION
q25.1
LOCUS TYPE
gene with protein product
VARIANTS
390
External Links
HGNC
Ensembl
NCBI
OMIM