CATSPER2 Gene
cation channel sperm associated 2
ALIAS SYMBOLS
None
Your Results
Sign InDescription
The CATSPER2 gene provides instructions for producing a protein that is found in the tail (flagellum) of sperm cells. The CATSPER2 protein plays a role in sperm cell movement (motility) and is required for sperm cells to push through the outside membrane of the egg cell during fertilization. The CATSPER2 protein is embedded in the membrane of the sperm tail and is necessary in order for positively charged calcium atoms (calcium cations) to enter the cell. Calcium cations are needed for a type of sperm motility called hyperactivation. Hyperactivation is characterized by vigorous movements of the sperm tail, which are required for the sperm to push through the membrane of the egg cell during fertilization.
CHROMOSOME
15
LOCATION
q15.3
LOCUS TYPE
gene with protein product
VARIANTS
21
External Links
HGNC
Ensembl
NCBI
OMIM