Variants
Sign InSign Up

FOXC1 Gene

forkhead box C1

ALIAS SYMBOLS

  • FREAC3

  • ARA

  • IGDA

  • IHG1

Your Results

Sign In

Description

The FOXC1 gene provides instructions for making a protein that attaches (binds) to specific regions of DNA and regulates the activity of other genes. On the basis of this action, the FOXC1 protein is called a transcription factor.

The FOXC1 protein plays a critical role in early development, particularly in the formation of structures in the front part of the eye (the anterior segment). These structures include the colored part of the eye (the iris), the lens of the eye, and the clear front covering of the eye (the cornea). Studies suggest that the FOXC1 protein may also have functions in the adult eye, such as helping cells respond to oxidative stress. Oxidative stress occurs when unstable molecules called free radicals accumulate to levels that can damage or kill cells.

The FOXC1 protein is also involved in the normal development of other parts of the body, including the heart, kidneys, and brain.

CHROMOSOME

6


LOCATION

p25.3


LOCUS TYPE

gene with protein product

VARIANTS

220

SEE THE VARIANTS →

Phenotypes

External Links

  • HGNC

    HGNC:3800

  • NCBI

    2296

  • OMIM

    601090

© 2024 Biocodify. All rights reserved.

TwitterTwitter

Product

HomePricingDashboard

Stay up to date

The latest news and updates from Biocodify, sent to your inbox.