MTOR Gene
mechanistic target of rapamycin kinase
ALIAS SYMBOLS
RAFT1
RAPT1
FLJ44809
Your Results
Sign InDescription
The MTOR gene provides instructions for making a protein called mTOR. This protein is found in various cell types throughout the body including brain cells. It interacts with other proteins to form two distinct protein groups, called mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). Both of these complexes transmit signals that direct the cells' function. Signaling through mTORC1 and mTORC2 regulate protein production, which influences cell growth, division, and survival. This mTOR signaling is especially important for growth and development of the brain, and it plays a role in a process called synaptic plasticity, which is the ability of the connections between nerve cells (synapses) to change and adapt over time in response to experience. Synaptic plasticity is critical for learning and memory.
CHROMOSOME
1
LOCATION
p36.22
LOCUS TYPE
gene with protein product
VARIANTS
1,292
External Links
HGNC
Ensembl
NCBI
OMIM