Variants
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TET2 Gene

tet methylcytosine dioxygenase 2

ALIAS SYMBOLS

  • FLJ20032

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Description

The TET2 gene provides instructions for making a protein whose function is unknown. Based on the function of similar proteins, researchers believe the TET2 protein is involved in regulating the process of transcription, which is the first step in protein production. Although this protein is found throughout the body, it may play a particularly important role in the production of blood cells from hematopoietic stem cells. These stem cells are located within the bone marrow and have the potential to develop into red blood cells, white blood cells, and platelets. The TET2 protein appears to act as a tumor suppressor, which is a protein that prevents cells from growing and dividing in an uncontrolled way.

CHROMOSOME

4


LOCATION

q24


LOCUS TYPE

gene with protein product

VARIANTS

86

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Phenotypes

External Links

  • HGNC

    HGNC:25941

  • NCBI

    54790

  • OMIM

    612839

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