Variants
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TNFRSF13B Gene

TNF receptor superfamily member 13B

ALIAS SYMBOLS

  • TACI

  • CD267

  • IGAD2

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Description

The TNFRSF13B gene provides instructions for making a protein called TACI. The TACI protein is found on the surface of immune system cells called B cells. These specialized white blood cells help protect the body against infection from foreign invaders such as bacteria and viruses. When B cells mature, they produce special proteins called antibodies (also known as immunoglobulins). Antibodies attach to specific foreign invaders, marking them for destruction. Through interactions with other proteins, TACI promotes cell signaling, plays a role in B cell survival and maturation, and is involved in the production of antibodies.

CHROMOSOME

17


LOCATION

p11.2


LOCUS TYPE

gene with protein product

VARIANTS

191

SEE THE VARIANTS →

Phenotypes

External Links

  • HGNC

    HGNC:18153

  • NCBI

    23495

  • OMIM

    604907

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