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Endometrial carcinoma

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Description

A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation.

NCI

  • Mode of Inheritance

  • Autosomal dominant inheritance
  • Somatic mutation

VARIANTS

207

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Genes

External Links

  • OMIM

    608089

  • Orphanet
  • HPO

    8545

  • Medgen

    C0476089

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