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Gastric adenocarcinoma and proximal polyposis of the stomach

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Description

Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is characterized by autosomal dominant transmission of fundic gland polyposis (FGP) with occasional hyperplastic and adenomatous polyps, sparing of the gastric antrum, and the development of intestinal-type gastric adenocarcinoma. Colorectal polyposis is not observed, and family history does not include colorectal cancer (Worthley et al., 2012).

OMIM

  • Mode of Inheritance

    VARIANTS

    4

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    Genes

    External Links

    • OMIM
    • Orphanet

      314022

    • HPO
    • Medgen

      C4749917

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