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Pleomorphic adenoma of salivary gland

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Description

A benign, slow-growing tumor composed of cells that demonstrate both epithelial and mesenchymal differentiation. It is the most common neoplasm of salivary gland origin, and mostly occurs in the parotid gland. The average age of patients has been reported to be 43 years; women are more often affected than men. The malignant change rate has been estimated to be 6%. The malignant counterpart is carcinoma ex pleomorphic adenoma.

NCI

  • Mode of Inheritance

  • Autosomal dominant inheritance
  • Somatic mutation

VARIANTS

0

Genes

External Links

  • OMIM

    181030

  • Orphanet

    454821

  • HPO
  • Medgen

    C1519176

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