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XFE progeroid syndrome

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Description

An autosomal recessive condition caused by mutation(s) in the ERCC4 gene, encoding DNA repair endonuclease XPF. it is characterized by characterized by cutaneous photosensitivity and progeroid features in multiple organ systems.

NCI

  • Mode of Inheritance

  • Autosomal recessive inheritance

VARIANTS

9

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Genes

External Links

  • OMIM

    610965

  • Orphanet
  • HPO
  • Medgen

    C1970416

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